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Biacore A100

Shortening timelines and reducing costs in biotherapeutic development - confident selection of mAbs

Enabling drug discovery - confident selection of LMW compounds

View the recorded webinar, "Improving efficiency in biotherapeutic development using Biacore A100"

View Applications or Publications:

Rapid kinetic analysis of hybridomas

384 hybridomas
Rapid kinetic screen
16 mAbs selected from kinetic screen
High resolution kinetics

Selectivity-based compound screening

1280 compounds - 2 targets
Sample-focused screen
60 compounds - 7 targets
Target-focused screen

"The Biacore A100 provides a substantial throughput increase for accurate determination of binding kinetics and affinities to help make lead choices much earlier in the discovery process".

Scott L. Klakamp, Ph.D., Senior Scientist, Abgenix, Inc., California.

"The multi-target protein panel approach in Biacore A100 is an excellent way to study complex drug targets and the chance to find biological activity is enhanced when performing these assays as the information obtained gives a clear picture on the mode of binding".

Dr. Walter Huber, F. Hoffman La-Roche, Basel, Switzerland

Download application material

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Application Note 83: A multi-protein panel approach for selectivity-based compound screening using Biacore A100 (754 kB)
Application Note 84: Early kinetic screening of hybridomas for confident antibody selection using Biacore A100 (2 MB)