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Key application areasBiacore™ T200 is a highly flexible, general purpose system that covers the broadest range of assay types, and also offers a number of functionality features that are of particular benefit to specific application areas. Examples of how the system supports a number of key application areas are described below. Characterization of biomolecular interactions in life science research
Biacore T200 provides comprehensive, high-quality characterization of biomolecules and their interactions, enabling key conclusions to be made with more confidence. With the highest sensitivity of any current Biacore system, Biacore T200 offers an outstanding level of perfomance to match your research ambitions, providing great flexibility together with exceptional data quality and highly sophisticated software support:
• Comprehensive characterization of biomolecular interactions - including kinetics, affinity, specificity and concentration
• Detailed analysis of structure-function relationships
• Increased understanding of molecular pathways and biological mechanisms
• Confident identification/selection of potential drug targets, diagnostic markers and research tools
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LMW drug discovery
Information-rich binding data on the interactions of LMW compounds with target proteins greatly assists confident decision making during the numerous stages of the drug discovery process. From sensitive, reliable detection of 1:1 binding together with selectivity information during compound screening to high resolution kinetic analysis in lead optimization and all stages in between, Biacore T200 delivers comprehensive, high quality data for drug discovery applications.
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Read more about this application - here >> |
Biotherapeutic Drug Discovery
Biacore systems are widely used in applications right across the biothereapeutic drug discovery and development workflow, from early screening right through to manufacturing and QC. Biacore T200 provides a powerful solution for the selection and optimization of therapeutic antibodies, providing high quality, comprehensive characterization data together with assay flexibility and low consumption of antibodies and antigen.
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Immunogenicity testing in pre-clinical/clinical drug development
The monitoring and characterization of anti-drug antibodies (ADAs) during the pre-cinical / clinical development process is essential to ensure the safety and efficacy of protein therapeutics. Biacore T200 directly supports assays for screening, confirmation and characterization of ADAs direct from serum samples, with software guidance for development of immunogenicity assays and ready-made solutions to deal with common problems for immunogenicity testing. Read more about immunogenicity testing with Biacore T200 - click here >>
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Concentration analysis in vaccine development & manufacture
The vaccine market has grown dramatically in recent years and the industry is under increasing presssure from regulatory authorities to further improve purity and safety. Production methods are also facing new challenges of scalability and timeline pressures to meet the emerging threats such as pandemics. Biacore T200 meets the demands of improved analytical capabilities in vaccine applications, providing reliable quantification of vaccine products and host cell impurities for rapid, safe vaccine development. Read more about vaccine applications with Biacore T200 - click here >>
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