Biacore J

This page is updated regularly. To find references and abstracts of all publications citing Biacore, go to Reference Database.

Kinetics and binding sites for interaction of the prefoldin with a group II chaperonin: contiguous non-native substrate and chaperonin binding sites in the archaeal prefoldin

M. Okochi, T. Nomura, T. Zako, T. Arakawa, R. Iizuka, H. Ueda, T. Funatsu, M. Leroux and M. Yohda

J Biol Chem 279: 31788-95 (2004)

On the interaction between prefoldins and group II chaperonins.  This is shown to be important in protein folding, assembly, transport, and degradation.  Contains an excellent explanation of the assay and analysis.

Link to abstract

Beacon interacts with cdc2/cdc28-like kinases

L. Kantham, L. Kerr-Bayles, N. Godde, M. Quick, R. Webb, T. Sunderland, J. Bond, K. Walder, G. Augert and G. Collier

Biochem Biophys Res Commun 304: 125-9 (2003)

A demonstration of how kinases (CLK1, 2, and 4)  interact with the “beacon” gene product, implied in the regulation of energy metabolism. Implications for treatment of obesity.

Link to abstract

Tanis: a link between type 2 diabetes and inflammation?

K. Walder, L. Kantham, J. S. McMillan, J. Trevaskis, L. Kerr, A. De Silva, T. Sunderland, N. Godde, Y. Gao, N. Bishara, K. Windmill, J. Tenne-Brown, G. Augert, P. Z. Zimmet and G. R. Collier

Diabetes 51: 1859-66. (2002)

A ligand for “tanis”, a novel liver protein, is identified by Y2-hybrid and binding is further characterized using Biacore J. Analysis partly performed in whole serum.

Link to abstract