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Biacore T100

View Applications or Publications:

Characterization of serum responses during development of immunotherapeutics

Comparison of Biacore & ELISA
Kinetic maturation of responses

Immunogenicity: Confident detection & characterization of anti-drug antibodies

Drug interference
Detecting low affinity ADAs

Selection of therapeutic antibody candidates using high-resolution kinetics

Kinetic analysis of candidates
On/off-rate mapping

Concentration analysis without the need for a standard
.

Calibration-free concentration analysis

Biacore T100 - Application Notes

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Application Note 79: Development of immunotherapeutics and immunization regimes (744 kB)
Application Note 80: Transition state thermodynamic analysis using Biacore T100 (448 kB)
Application Note 81: Selection of protein therapeutic candidates using Biacore T100 (474 kB)