The diversity and high specificity of the antibody-antigen interaction, coupled with the ability to manipulate the characteristics of the interaction, have created many uses for antibodies and antibody fragments. Within research and drug discovery, for example, antibodies are used to help unravel the details of biological mechanisms and identify therapeutic targets.
Clearly defining interaction characteristics ensures that the best antibodies are selected as research tools or assay components.
Biacore systems enable the comprehensive characterization of antibodies to be completed within days rather than months. Based on the initial characterization data, antibodies can be selected or modified to suit the requirements for the application. The ability to work directly with crude samples, such as hybridoma supernatants, also makes Biacore systems ideal for applications in monoclonal antibody development.
No other solution provides so much information and without labels - specificity, kinetics, affinity, and epitope mapping.
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