"Over 4000 peer-reviewed scientific publications have used Biacore systems to study protein interactions"

Native and recombinant proteins are used extensively from investigations of disease pathways through to the identification of protein targets for potential drug therapies.

Proteins from normal and diseased tissues can be compared and, using recombinant technology, variations of the proteins of interest can be produced as part of the effort to understand their functionality or to deduce the structure of potential drug candidates.

No other solution provides so much information from a single instrument - specificity, kinetics, affinity, and thermodynamic measurements.

For those interested in the in-depth study of binding mechanisms and the role of non-covalent forces involved in complex formation, Biacore T100 is well suited for investigating the thermodynamics of an interaction. Excellent temperature control and buffer degassing facilitate accurate, detailed characterization of transition state formation during association and dissociation phases

For scientists taking the ‘proteomics approach’ to studying disease pathways and identifying potential drug targets Biacore 3000, with its ability to isolate and characterize proteins that can be recovered under ideal conditions and deposited direct to MALDI target for analysis by mass spectrometry, is a great advantage particularly since they often work with very small amounts of unknown proteins.